PRESS RELEASE

07.07.2015

Epic Sciences expands partnership with LabCorp to provide circulating tumor cell analysis and support oncology clinical trials in Asia.

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Epic’s technology provides in-depth information to match treatments and monitor treatment effectiveness for clinical trials of targeted therapies and for companion diagnostic development.

Epic Sciences (Epic) announced today an agreement with Laboratory Corporation of America® Holdings (LabCorp®) (NYSE: LH) to provide circulating tumor cell (CTC) technology and support oncology clinical trials in Asia through Covance Drug Development (Covance). Covance will process patient samples in Singapore, and then send samples to Epic’s clinical laboratory in San Diego, which has recently been licensed under the Clinical Laboratory Improvement Amendments (CLIA) of 1988, for downstream detection and molecular characterization of CTCs. This agreement expands on a previous contract announced last year between Epic and LabCorp for European clinical trials.

“The expansion of the partnership with LabCorp will provide an important access point for all oncology clinical trials conducted in Asia and meet the global demand for Epic’s circulating tumor cell technology,” said Murali Prahalad, Ph.D., president and CEO of Epic Sciences. “For Epic’s clinical trial partners and customers, we provide significant, actionable information on patient matching, treatment effectiveness and disease progression to streamline clinical trials for new targeted cancer therapies and to develop essential companion diagnostics.”

“We are excited to expand access to Epic’s circulating tumor cell technology from Europe to Asia,” said Dr.Steven M. Anderson, chief scientific officer of Covance Drug Development. “Epic’s technology, which can robustly and reproducibly detect, quantitate and molecularly characterize circulating tumor cells, is a significant tool available to support oncology clinical trials.”

Epic is developing new, high-definition diagnostic tests to provide clinically relevant information about how a patient’s cancer changes over time, which will allow for improved therapy selection and early drug resistance detection. From a simple blood draw, Epic’s “no cell left behind” technology analyzes approximately six million cells across more than 90 parameters to capture and analyze all possible types of circulating tumor cells. Unlike other blood-based biomarkers used in liquid biopsies, CTCs hold both genetic and proteomic information and encompass the profiles of both primary tumors and metastases. Epic’s technology can incorporate CTC enumeration, quantitative protein biomarker analysis and single-cell genomic analysis by next generation sequencing (NGS) or fluorescent in situ hybridization (FISH) to give a comprehensive picture of a patient’s cancer.

LabCorp is the world’s leading healthcare diagnostics company, providing comprehensive clinical laboratory services through LabCorp Diagnostics, and end-to-end drug development support through Covance Drug Development. With combined revenue proforma for the acquisition of Covance in excess of $8.5 billion in 2014 and more than 48,000 employees in over 60 countries, LabCorp offers innovative solutions to healthcare stakeholders, including physicians, patients and consumers, biopharmaceutical companies, government agencies, managed care organizations, hospitals, and clinical labs.

About Epic Sciences

At Epic Sciences, we develop clinically proven predictive tests to detect and monitor cancer at the individual cell level. With a proprietary rare-cell detection engine, we provide insights to clinical, biotech, pharmaceutical and academic teams on how cancer emerges, mutates and remits so they can make pivotal decisions at every point in patient treatment with greater certainty. Recognizing the unique nature of each person’s cancer, we offer truly personalized diagnostic tests, while being non-invasive for the patient.

We have developed the first clinically proven predictive test for metastatic castration-resistant prostrate cancer (mCRPC), the Epic AR-V7 test. Using the same rare-cell detection platform and Epic’s biobank of over 30,000 blood samples, each profiled with predictive biomarkers, we partner with leading pharmaceutical and biotechnology companies, major cancer centers, the National Cancer Institute (NCI), and the National Institutes of Health (NIH) to pursue additional predictive tests for breast, ovarian, colon and other cancers and diseases. Our mission is to revolutionize cancer care and therapies to make them as precise, safe and life-sustaining as humanly possible.

For more information, visit epicsciences.com.

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Epic Sciences Media Contact: Jessica Yingling, Ph.D., Little Dog Communications Inc., jessica@litldog.com,+1.858.344.8091