PUBLICATION AND RESOURCES

PUBLICATIONS

7.1.2020 | Clinical Cancer Research
SLFN11 Expression in Advanced Prostate Cancer and Response to Platinum-based Chemotherapy.

Conteduca V, Ku SY, Puca L, Slade M, Fernandez L, Hess J, Bareja R, Vlachostergios PJ, Sigouros M, Mosquera JM, Sboner A, Nanus DM, Elemento O, Dittamore R, Tagawa ST, Beltran H.Mol Cancer Ther. 2020 May;19(5):1157-1164. DOI: 10.1158/1535-7163
7.1.2020 | Clinical Cancer Research
Single-Cell Circulating Tumor Cell Analysis Reveals Genomic Instability as a Distinctive Feature of Aggressive Prostate Cancer.

Malihi PD, Graf RP, Rodriguez A, Ramesh N, Lee J, Sutton R, Jiles R, Ruiz Velasco C, Sei E, Kolatkar A, Logothetis C, Navin NE, Corn P, Aparicio AM, Dittamore R, Hicks J, Kuhn P, Zurita AJ.Clin Cancer Res. 2020 Apr 27. DOI: 10.1158/1078-0432.CCR-19-4100
5.30.2019 | JCO Precision Oncology
Circulating Tumor Cells as a Predictor of Treatment Response in Clinically Localized Prostate Cancer

Using nonenrichment-based, potentially more sensitive Epic Sciences circulating tumor cell (CTC) platform, we sought to detect and characterize CTCs in untreated, high-risk localized prostate cancer and to evaluate their clinical implication.
3.20.2019 | Science Translational Medicine
Delta-like protein 3 expression and therapeutic targeting in neuroendocrine prostate cancer

Delta-like protein 3 expression and therapeutic targeting in neuroendocrine prostate cancer. Science Translational Medicine 20 Mar 2019. DOI: 10.1126/scitranslmed.aav0891
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Resources

SCIENTIFIC POSTERS

9.25.2020
Evaluating Biomarkers in Metastatic Castration Resistant Prostate Cancer (mCRPC) Patients (Pts) Treated with Enzalutamide (Enza): PSA, Circulating Tumor Cell Counts, AR-V7 Status, PET Imaging vs. CT and Tc99 Scans.
5.29.2020
Prevalence and tissue concordance of BRCA2 copy number loss evaluated by single-cell, shallow whole-genome sequencing of circulating tumor cells (CTCs) in castration-resistant prostate cancer (CRPC).
5.29.2020
Circulating tumor cells (CTCs) with small-cell like features are prevalent in metastatic castration resistant prostate cancer (mCRPC) and show selective pharmacodynamic reductions in patients treated with platinum therapy but not an ARSi or taxane.
5.29.2020
Clinical significance of CTC enumeration on the Epic Sciences platform in metastatic castration-resistant prostate cancer (mCRPC) patients treated with AR signaling inhibitors (ARSi).
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PACKAGE INSERTS

AR-V7 Blood Collection Kit Package Insert (Kit FM-00049 and FM-00076)
CE Mark Blood Collection Kit Package Insert (Kit FM-000107)
CTC Liquid Biopsy Blood Collection Kit Requisition Form (LBL-00081)
ALL INSERTS

EPIC PODCAST: FEATURED

6.13.2019
EPISODE 02 | LAUREN LEIMAN

In Episode 2 of Innovations in Cancer, we speak with Lauren Leiman, executive director at BloodPAC, the Blood Profiling Atlas in Cancer (BloodPAC) Consortium, launched October 2017, to accelerate the development and validation of liquid biopsy assays to improve the outcomes of patients with cancer. Lauren discusses the collaborative infrastructure that enables sharing of information between stakeholders in industry, academia, and regulatory agencies with the goal to standardize liquid biopsies to improve outcomes for patients.

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